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Human papillomavirus (HPV) vaccine education

Evidence Rating

Insufficient Evidence

Health Factors

Educational efforts inform young women and men about HPV and its consequences as well as the benefits of vaccinating against the disease. Education may be provided in person, by telephone, in writing, or by other media such as videos. HPV vaccines protect against HPV and cervical cancer; one additionally protects against genital warts. Vaccines are most effective in individuals who receive a full course (3 doses) and have no previous HPV (, Rambout 2007).

Expected Beneficial Outcomes (Rated)

  • Increased vaccination

Other Potential Beneficial Outcomes

  • Increased HIV and STI knowledge

  • Reduced incidence of HPV

Evidence of Effectiveness

There is insufficient evidence to determine whether educational efforts increase HPV vaccination rates among eligible adolescent girls and young women (), though greater vaccine-related knowledge is associated with higher uptake (). Available evidence indicates that educational interventions may increase HPV knowledge and vaccination intentions among both young women (, , ) and men (), including black men and women (), and that tailoring the intervention to a specific audience may strengthen effects (). Provider recommendation of the vaccine increases acceptability () and uptake (Kester 2013, ). Additional evidence is needed to confirm effects.

There is no evidence that receipt of the HPV vaccine increases sexual risk behavior among adolescent girls and young women (, ).

Impact on Disparities

No impact on disparities likely

Implementation Resources

CDC-HPV professional resources - Centers for Disease Control and Prevention (CDC). Professional resources: Resources for health professionals.

Citations - Evidence

* Journal subscription may be required for access.

Gerend 2013* - Gerend MA, Shepherd MA, Lustria MLA. Increasing human papillomavirus vaccine acceptability by tailoring messages to young adult women’s perceived barriers. Sexually Transmitted Diseases. 2013;40(5):401–5.

Kessels 2012* - Kessels SJ, Marshall HS, Watson M, et al. Factors associated with HPV vaccine uptake in teenage girls: A systematic review. Vaccine. 2012;30(24):3546–56.

Kester 2014* - Kester LM, Shedd-Steele RB, Dotson-Roberts CA, Smith J, Zimet GD. The effects of a brief educational intervention on human papillomavirus knowledge and intention to initiate HPV vaccination in 18-26 year old young adults. Gynecologic Oncology. 2014;132(Suppl 1):S9–12.

Krawczyk 2012* - Krawczyk A, Lau E, Perez S, et al. How to inform: Comparing written and video education interventions to increase human papillomavirus knowledge and vaccination intentions in young adults. Journal of American College Health. 2012;60(4):316–22.

Mayhew 2014* - Mayhew A, Mullins TLK, Ding L, et al. Risk perceptions and subsequent sexual behaviors after HPV vaccination in adolescents. Pediatrics. 2014;133(3):404–11.

Rysavy 2014* - Rysavy MB, Kresowik JD, Liu D, et al. Human papillomavirus vaccination and sexual behavior in young women. Journal of Pediatric and Adolescent Gynecology. 2014;27(2):67–71.

Brewer 2007* - Brewer NT, Fazekas KI. Predictors of HPV vaccine acceptability: A theory-informed, systematic review. Preventive Medicine. 2007;45(2-3):107-14.

Kester 2013 - Kester LM, Zimet GD, Fortenberry JD, Kahn JA, Shew ML. A national study of HPV vaccination of adolescent girls: Rates, predictors, and reasons for non-vaccination. National Institutes of Health Public Access (NIH). 2014;17(5):879-885.

Date Last Updated

Oct 24, 2014